硕士生导师、教授名单

陈铭

发布时间：2021-08-25浏览次数：7566

教授：陈铭

Email:chenming0228@cczu.edu.cn

个人主页：https://www.x-mol.com/groups/chenming


教育经历:

  • 2006/09-2010/06，苏州大学 材料与化学化工学部，学士学位.

  • 2010/09-2015/06，中国科学院上海有机化学研究所，博士学位. 导师：刘元红 研究员


工作经历：

  • 2015/07-2016/06，中国科学院上海有机化学研究所, 刘元红研究员课题组 研究助理.

  • 2016/08-2020/11, 美国芝加哥大学，博士后，导师： Prof. Guangbin Dong.

  • 2021/03-至今，德赢vwin官方入口，教授


个人荣誉：

  1. 2021年，入选江苏省特聘教授

  2. 2015 年，刘铸晋优秀博士生奖学金；

  3. 2015 年，中国科学院大学优秀毕业生；

  4. 2015 年，北京市普通高等学校优秀毕业生；

  5. 2014 年，中国科学院大学三好学生；

  6. 2014 年，中国科学院大学优秀学生干部；


社会兼职（社会兼职填是否担任过专业杂志编委、专业委员会委员、专业协会会员等）

  • ******

  • ******


研究方向:

  • 围绕有机化学为中心，旨在解决有机合成化学中长期存在的挑战性课题。

  • 主要以过渡金属催化为手段，通过设计合成新型的催化剂、配体，发展高活性、

  • 实用的有机合成方法学，实现一些重要的（手性）合成砌块的高效合成。


教学科研项目:

  • 教学：基础化学实验，研究生波谱分析（理）

  • 科研项目：国自然青年科学基金项目，领军型创新人才引进培育项目C类


发表论文:

  • Publications inCCZU:

  1. Yang, Sen.; Fan, Huike.; Xie, Licheng.; Dong, Guangbin.; and Chen, Ming.*Photo-induced Desaturation of Amides by Palladium Catalysis.Org. Lett.2022, 24, 6460-6465.

  1. Fan, Huike, Yang, Sen.; Li, Junhua.; Teng, Qiaoqiao.; and Chen, Ming.*BaO-Catalyzed α-Deuteration of Ketones, Sulfones, Sulfoxides, and Nitriles.Eur. J. Org. Chem.2022, e202201218.

  1. Du, Yujia.; Sheng, Xiaxin.; Li, Junhua.; Chen, Jiaming.; Yang, Sen. *; and Chen, Ming.*Aryl-to-Alkyl Radical Relay Heck Reaction of Amides with Vinyl Arenes.Chem. Sci., 2023, 14, 3580-3586.

  1. Sheng, Xiaxin.; Du, Yujia.; Li, Junhua.; Teng, Qiaoqiao.*; and Chen, Ming.*Photo-induced Nitrogen-to-Alkyl Radical Relay Heck Reaction of o-Alkylbenzamide with Vinyl Arenes by Palladium Catalysis. Org. Lett.2023, 25, 3664-3669.

  1. Yang, Sen.; Guo-ying, Liu.; Fan, Huike.; Jun-hua, Li.; Teng, Qiaoqiao*.; and Chen, Ming.* Sodium Hydroxide (NaOH)-Mediated Oxidative Hydroxylation of Arylboronic Acids and Its Applications in C-O Bond Formation. Eur. J. Org. Chem.2023, e202300517.(Dedicated to celebrate the 45th anniversary of Changzhou University)

  1. Li, Pei-shang.; Teng, Qiaoqiao*.; and Chen, Ming.* Photoinduced Radical Cascade Domino Heck Coupling of N-Aryl Acrylamide with Vinyl Arenes Enabled by Palladium Catalysis. Chem. Commun. 2023, 59, 10620-10623.

  1. Chen, Jia-ming.; Li, Jun-hua.; Xie, Li-cheng.; Fan, Hui-ke.; Sheng, Xia-xin.; Du, Yu-jia.; Liu, Guo-ying.; Hu, Hao.; Jiang, Yan*.; and Chen, Ming.* Iron-Catalyzed Divergent Approach to Naphthyridinones and Quinolinones: Leveraging Povarov and Carbonyl-Alkyne Metathesis Reactions of Electron Deficient Alkynes.Org.Chem. Front.2023,10, 5505-5511.

  1. Yang, Sen.; Hu, Hao.; and  Chen, Ming.*  Photoinduced Palladium-Catalyzed Regio- and Chemoselective Elimination of Primary Alkyl Bromides: A Mild Route to Synthesize Unactivated Terminal Olefins.Org. Lett. 2023, 25, 7968-7973.

  1. Yang, Sen.; Hu, Hao.; Li, Jun-hua and  Chen, Ming.* Direct Alkylation of Glycine Derivatives via Photoinduced Palladi-um Catalysis, Utilizing Intermolecular Hydrogen Atom Transfer Mediated by Alkyl Radicals. ACS Catalysis.2023, 13, 15652−15662. DOI:10.1021/acscatal.3c04075.

  1. Tang, Lu-ning.; Liu, Guo-ying.; Li, Jun-hua and  Chen, Ming.* Palladium-Catalyzed Diversified Synthesis of mono-Fluorinated Alkenes from Allylic gem-Difluorides through Pd-OH intermediate. Org. Lett.2023, 25, 9064-9069.

  1. Du,Yu-jia†, Sheng, Xia-xin†, Tang, Lu-ning, Chen, Jia-ming, Liu, Guo-ying, Hu, Hao, Yang, Sen*, Zhu Lei*, and Chen, Ming.*Accessing Benzoazepine Derivatives via Photoinduced Radical Relay Formal [5+2] of Amide/Alkyne Enabled by Palladium Catalysis. Org. Lett. 2024, 26, 2662-2667.

  1. Liu, Guo-ying+, Tang, Lu-ning+*, Li, Jun-hua, Yang, Sen* and Chen, Ming*. Palladium-Catalyzed Alkynylation of Allylic gem-Difluorides. Chem. Commun.2024,60, 4471-4474.

  1. Yang, Sen.;+, Cai, Sha-sha.;+, Li, Jun-hua andChen Ming.*Photoinduced Palladium -Catalyzed Radical Heck-Type Coupling of Cyclobutanone Oxime Esters with Vinyl Arenes.J. Org. Chem. 89, 7243-7254.

  1. Zhan, Yan-fang+.; Jia-ming Chen+.; Sheng, Xia-xin.; Qiu, Chao-ying.; Jiang, Yan*, Yang, Sen*.; and Chen Ming*.  Photoinduced Copper Catalyzed Nitrogen-to-Alkyl Radical Relay Sonogashira-type Coupling of o-Alkylbenzamides with Alkynes. Chem. Commun. 2024, 60, 7906-7909. .

  1. Sheng, Xia-xin.;† Qiu, Chao-ying.;† Wang, Li-na .;† Du, Yu-jia.; Tang, Lu-ning.; Chen, Jia-ming.; Liu, Guo-ying.; Yang, Sen*, Zheng, Peng-fei*.; and Chen, Ming*.  Transition-Metal-Free Radical Relay Cascade Annulation of Amides: Access to Antitumor Active Benzo[b]azepine and Oxindole Derivatives. Chem. Eur. J. 2024, e202402402. DOI: 10.1002/chem.202402402.

  1. Wang, Huan†.; Wang, Yi-bin†.; Zhan, Yan-fang.; Zhu, Yi-ting.; Jiang, Yan*.; Yang, Sen*.; and Chen, Ming* Copper-Catalyzed Oxidative α-Double Bond Construction in α-Amino Carbonyl Compounds via Homo-Coupling with Arylamine Release.Org. Lett.2024, 26, 8128−8133.

  1. Yang, Sen+, Qiu, Chao-Ying+, Hu, Hao, Jiang, Yan* and Chen Ming*. Visible-Light-Driven Synthesis of N-Alkyl α-Amino Acid Derivatives from Unactivated Alkyl Bromides and in situ Generated Imines.Org. Lett.2024, 26, 8416−8423.

  1. Chen, Sheng-yu, Tang, Lu-ning*, and Chen, Ming*. Palladium-Catalyzed Double ipso-Defluoroetherification of Allylic gem-Difluorides with Phenols or Alcohols.

Org. Lett.2024, 26, 9799-9803.

  1. Xu, Cheng-zhi+, Xu, Zhen-yan+, Chen, Yi-feng*, Chen Ming* and Liu, Yuan-hong*.  Intermolecular Nitrile 1,2-Difunctionalization via Redox Gold Catalysis.Chem. Eur. J.2025, e202404368.

  1. Tang Lu-ning, Miao Jia-cheng, and Chen Ming*. Recent advances in Photoinitiated Pd-Catalyzed Desaturation and Heck-Type Reactions via 1,5-Hydrogen Atom Transfer. （Feature Article）Chem. Commun.2025, 61, 4621-4629.

  • Publications prior to CCZU:

1. Chen, M.; Chen, Y.; Sun, N.; Zhao, J.; Liu, Y.* Gold-Catalyzed Oxidative Ring Expansion of 2-Alkynyl-1,2-Dihydropyridines or -quinolines: Highly Efficient Synthesis of Functionalized Azepine or Benzazepine Scaffolds. Angew. Chem. Int. Ed.2015,54, 1200.

2. Chen, M.; Dong, G.* Direct Catalytic Desaturation of Lactams Enabled by Soft Enolization.J. Am. Chem. Soc.2017, 139, 7757. (Highlighted by Org. Process Res. Dev. 2017, 21, 1873.)

3. Chen, M.; Liu, F.; Dong, G.* Direct Palladium-Catalyzed β-Arylation of Lactams. Angew. Chem. Int. Ed. 2018,57, 3815.

4. Chen, M; Rago, A; Dong, G* Platinum-Catalyzed Desaturation of Lactams, Ketones and Lactones.  Angew. Chem. Int. Ed. 2018, 57, 16205. (Highlighted by Synfacts, 2019, 173)

5. Chen, M.; Dong, G.* Copper-Catalyzed Desaturation of Lactones, Lactams and Ketones under pH-Neutral Conditions.J. Am. Chem. Soc.2019, 141, 14889.

6. Chen, M.; Dong, G.* Platinum-catalyzed α,β-Desaturation of Cyclic Ketones through Direct Metal-enolate Formation. Angew. Chem. Int. Ed. 2021, 60, 7956.

7. Chen, M.; Chen, Y.; Liu, Y.* Palladium-catalyzed highly efficient synthesis of tetracenes and Pentacenes.Chem. Commun.2012, 48, 12189.

8. Chen, M.; Liu, J.; Wang, L.; Zhou, X.; Liu, Y.* Gold-catalyzed cascade cycloisomerization of 1,7-diyn-3,6-bis(propargyl carbonate)s: stereoselective synthesis of naphtho[b]cyclobutenes.Chem. Commun.2013, 49, 8650.(Highlighted by Synfacts, 2014, 144)

9. Chen, M.; Sun, N.; Liu, Y.*Environmentally Benign Synthesis of Indeno[1,2-b]quinolines via an Intramolecular Povarov Reaction.Org.Lett.2013, 15, 5574.

10. Chen, M.; Sun, N.; Xu, W.; Zhao, J.; Wang, G.; Liu, Y.* Gold-Catalyzed Ring Expansion of alkynyl heterocycle via 1,2-Migration of an Endocyclic C-Heteroatom Bond. Chem. Eur. J,2015, 21, 18571.

11. Chen, M†.; Sun, N†.; Chen, H.; Liu, Y.* Dioxazoles, a new mild nitrene transfer reagent in gold catalysis: highly efficient synthesis of functionalized oxazoles. Chem. Commun.2016, 52, 6324.

12. Chen, Y.; Chen, M.; Liu, Y.* Gold-Catalyzed Cyclization of 1,6-Diyne-4-en-3-ols: Stannyl Transfer from 2-Tributylstannylfuran Through Au/Sn Transmetalation.Angew. Chem. Int. Ed.2012, 51, 6181.

13. Chen, Y.; Chen, M.; Liu, Y.* Gold-Catalyzed Cascade Cyclizations of 1,6-Diynyl Carbonates to Benzo[b]fluorenes Involving Arylation of Oxocarbenium Ion Intermediates and Decarboxylative Etherification.Angew. Chem. Int. Ed.2012, 51, 6493. (Highlighted by  Synfacts2012, 969).

14. Sun, N.; Chen, M.; Liu, Y.* Gold-Catalyzed Oxidative Reactions of Propargylic Carbonates Involving 1,2-Carbonate Migration: Stereoselective Synthesis of Functionalized Alkenes. J. Org. Chem,2014, 79, 4055.

15. Liu, J.; Chen, M.; Zhang, L.; Liu, Y.* Gold(I)-Catalyzed 1,2-Acyloxy Migration/[3+2] Cycloaddition of 1,6-Diynes with an Ynamide Propargyl Ester Moiety: Highly Efficient Synthesis of Functionalized Cyclopenta[b]indoles. Chem. Eur. J.2015, 21, 1009.

16. Li, X.; Chen, M.; Xie, X.; Sun, N.; Li, S*.; Liu, Y*. Synthesis of Multiple-Substituted Pyrroles via Gold(I)-Catalyzed Hydroamination/Cyclization Cascade. Org. Lett.2015, 17, 2984.

17. Sun, R.; Liu, J.; Yang, S.; Chen, M.; Sun, N.; Chen, H.; Xie, X.; You, X.; Li, S.; Liu, Y.* Cp2TiCl2-Catalyzed cis-Hydroalumination of Propargylic Amines with Red-Al: Stereoselective Synthesis of Z-Configured Allylic Amines. Chem. Commun.2015, 51, 6426.

18. Xu, W.; Chen, M.; Sun, N.; Liu, Y.* Gold-catalyzed cyclization of 1,6-diynyl dithioacetals via 1,7-carbene transfer and aromatic C–H functionalization.Chem. Commun.2016, 52, 11000.

19. Hu, H†.; Hu, X†.; Chen, M.; Sun, N.;* Liu, Y.* Gold-Catalyzed Ring Expansion Reaction: Highly Efficient Synthesis of Functionalized 2,3-Benzodiazepine Scaffolds.Chin. J. Org. Chem.2018, 38, 190.



授权专利

  1. 专利：一种α-氘代酮、腈、亚砜类化合物的制备方法. 陈铭，樊慧柯. 申请号：202210465715.9. 公开号：CN114773174A. (授权)

  2. 专利：一种烯丙基单氟化合物的合成方法.陈铭，刘国营，唐路宁. 申请号：202310058291.9. 公开号：CN116003211A.

  3. 专利：可见光驱动非天然氨基酸及其衍生物的合成方法. 杨森;陈铭;胡浩. 申请号：202310791881.2. 公开号：CN116813490A

  4. 专利：抗肿瘤活性分子苯并[b]氮杂卓衍生物及其合成方法和应用. 陈铭;杜俞佳;盛夏鑫. 申请号：202311141245.1. 公开号：CN 117263861 A

  5. 专利：单氟1，4-烯炔类化合物的合成方法. 陈铭;刘国营. 申请号：202311476602.X

  6. 专利：可见光诱导一锅法三组分N-烷基非天然氨基酸衍生物的合成方法. 杨森;陈铭;胡浩; 裘超颖. 申请号：202410630543.5. 公开号：CN 118598762 A.

  7. 专利：菲环芳烃衍生物的一步合成方法. 陈铭; 李培商; 周琛. 申请号：202411572565.7.

8. 刘元红，陈铭，陈宜峰, 并四苯及并五苯类化合物的合成方法, 中国发明专利,申请号: 201210359027. 申请日期：2012-9-24. 专利号：CN103664499A.  (导师为第一作者)






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